2,2,6,6-四甲基哌啶基氯化锌氯化锂络合物,以 17% 浓度的四氢呋喃溶液 (0.7 M) 形式提供
C9H18NZnCl · LiCl
芳烃和杂环芳烃的选择性去质子化。
人们通常使用有机锂化合物或有机锂酰胺来锂化芳烃和杂芳烃,从而实现去质子化(例如 LDA)。这些试剂的高反应性和亲核性往往会导致不必要的副反应,并导致酯或酮等敏感官能团的出现。此外,这种去质子化反应通常需要低温,从而导致大规模生产成本更高。
锌酰胺的动力碱性较低,因此能在具有多种官能团的情况下稳定存在。
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