Phenylmagnesium Bromide, typ. 15 % solution in THF (typ. 0.8 M)
C6H5BrMg
Phenylmagnesium Bromide (CAS 100-58-3) is an organomagnesium compound (Grignard reagent) with molecular formula C6H5BrMg. It is supplied as a typical 15% solution in THF.
In organic synthesis it is used in Grignard-type reactions as a reactive carbon nucleophile.
Phenylmagnesium Bromide reacts readily with moisture and oxygen and should be handled under dry, inert conditions. Consult the SDS and site-specific procedures for compatible materials, fire response, and storage.
Applications
Grignard-reactions: reagent for the introduction of the phenyl group.
Specifications
- Phenylmagnesium Bromide: 14.0 – 16.0 %
Method of Analysis
Determination of assay as total base by acidimetric titration after hydrolysis; detailed description available on request.Handling Instructions
Handling Phenylmagnesium Bromide should only be handled under inert gas atmosphere. Avoid contact with eyes, skin and clothes as well as inhalation. Vapors may form explosive mixtures with air. Vapors are heavier than air and may spread along floors. Flash-back possible over considerable distance. Use only explosion-proof equipment. Take measures against electrostatic discharges. Protect from frost, heat and sunlight. Never add water, acids or oxidizing materials to the product. In case of fire use dry extinguishers on basis of sodium chloride or limestone powder. Never use water or CO2-extinguishers. Pay attention to the safety data sheet.
Storage Instructions
As material tends to crystallize it should be stored above 20 °C. Precipitates can be redissolved by warming and appropriate homogenization. Keep container dry and tightly closed. When stored according to SDS the material is fairly stable. We still recommend to retest the material 6 months after date of analysis if included on CoA. If not included, use the date of manufacturing for the calculation.
Legal Disclaimer
The information presented herein is believed to be accurate and reliable but is presented without guarantee or responsibility on the part of Albemarle Corporation and its subsidiaries and affiliates. It is the responsibility of the user to comply with all applicable laws and regulations and to provide for a safe workplace. The user should consider any health or safety hazards or information contained herein only as a guide and should take those precautions which are necessary or prudent to instruct employees and to develop work practice procedures in order to promote a safe work environment. Further, nothing contained herein shall be taken as an inducement or recommendation to manufacture or use any of the herein materials or processes in violation of existing or future patent.