2,2,6,6-四甲基哌啶基氯化镁氯化锂复合物以 20% 浓度的四氢呋喃/甲苯溶液 (1.0 M) 形式提供
芳烃和杂芳烃的选择性去质子化。
芳烃和杂芳烃通常通过使用有机锂化合物或有机锂酰胺(例如 LDA)直接进行锂化,实现去质子化。这些试剂具有高反应性和亲核性,常会导致不必要的副反应,并导致酯或酮等敏感官能团的出现。此外,这种去质子化反应通常需要在低温条件下进行,导致大规模生产成本较高。
镁酰胺的动力碱性较低,因此能在具有多种官能团的情况下稳定存在。
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