Lithium Bromide, typ. 30 % solution in THF (typ. 4.1 M)
LiBr
Lithium Bromide (CAS 7550-35-8) is an inorganic lithium salt with molecular formula LiBr. It is supplied as a typical 30% solution in THF.
The solution of LiBr in THF was developed mainly for application in organic synthesis, especially as an additive for organometallic transformations. Furthermore, it can be used as bromination reagent or as a weak Lewis acid.
Store in a tightly sealed container to prevent contamination (and moisture pickup where applicable). Use standard industrial hygiene practices and consult the SDS for handling, incompatibilities, and spill response.
Applications
The solution of LiBr in THF was developed mainly for application in organic synthesis, especially as an additive for organometallic transformations. Furthermore, it can be used as bromination reagent or as a weak Lewis acid. In combination with transition metal salts an efficient catalyst for cross-coupling reactions can be formed. References: Charette, A: in Encyclopedia of Reagents for Organic Synthesis, Paquette, L.A.,Ed., John Wily and Sons: New York (1995), Vol. 5, 3049. Wietelmann, U. in Science of Synthesis, Vol. 8a, Majewski, M. Snieckus, V-. Vol. Eds., Georg Thieme Verlag, Stuttgart, New York (2006), pp 139 – 164.
Specifications
- LiBr: 29,0% - 31,0%
Method of Analysis
Determination of assay by argentometric titration of bromide; detailed description available on request.
Handling Instructions
THF can form explosive peroxides in contact with air. Storage and handling under inert gas is recommended. Vapors may form explosive mixtures with air. Vapors are heavier than air and may spread along floors. Flash back possible over considerable distance. Take measures to prevent the build up of electrostatic charge. Use only explosion-proof equipment. Protect from frost, heat and sunlight. Never add oxidizing materials.
Storage Instructions
As LiBr tends to crystallize from the solution material should be stored above 15 °C. When stored according to SDS the material is fairly stable. We still recommend to retest the material 6 month after date of analysis if included on CoA. If not included, use the date of manufacturing for the calculation. Pay attention to official safety regulations (see also: ”Transport regulations” and “Marking“).
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