tert-Butylmagnesium Chloride, typ. 20 % solution in THF (typ. 1.7 M)

tert-Butylmagnesium Chloride, typ. 25 % solution in Diethyl Ether (1.7 M)

C4H9ClMg

CAS Number:  677-22-5 EC Number:  211-638-6 REACH Number:  01-2120102495-64-0000

tert-Butylmagnesium Chloride (CAS 677-22-5) is an organomagnesium compound (Grignard reagent) with molecular formula C4H9ClMg. It is supplied as a typical 25% solution in Diethyl Ether.

In organic synthesis it is used in Grignard-type reactions as a reactive carbon nucleophile or in deprotonation reactions as a base.

tert-Butylmagnesium Chloride reacts readily with moisture and oxygen and should be handled under dry, inert conditions. Consult the SDS and site-specific procedures for compatible materials, fire response, and storage.

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Physical and Chemical Properties
Property Value
IUPAC Name
magnesium;2-methylpropane;chloride
Molecular Weight
116.87g/mol
Appearance
Liquid
Color
Dark Brown
Crystallization Temperature
<= -10 °C
Flash Point
-45 °C 1,013 hPa (Diethyl ether)
Boiling Point
ca. 34.7 °C at 1,013 hPa (Diethyl ether)
Density
0.8 g/cm3 at 20 °C
Solubility in Water
(Not applicable)
Thermal Stability
Crystallization below around -10 °C

Applications

Grignard-reactions: reagent for the introduction of the tert-Butyl group. As base for deprotonation reactions. Strong, weakly nucleophilic base for deprotonation reactions.

Specifications

  • tert-Butylmagnesium Chloride: 24,0 - 26,0 %

    Method of Analysis

    Determination of assay as total base by acidimetric titration after hydrolysis; detailed description available on request.

    Handling Instructions

    Organomagnesium compounds should only be handled under inert gas atmosphere. Avoid contact with eyes, skin and clothes as well as inhalation. Vapors may form explosive mixtures with air. Vapors are heavier than air and may spread along floors. Flash-back possible over considerable distance. Use only explosion-proof equipment. Take measures against electrostatic discharges. Protect from frost, heat and sunlight. Never add water, acids or oxidizing materials to the product. In case of fire use dry extinguishers on basis of sodium chloride or limestone powder. Never use water or CO2-extinguishers. Pay attention to the safety data sheet.

    Storage Instructions

    When stored according to SDS the material is fairly stable. We still recommend to retest the material 9 months after date of analysis if included on CoA. If not included, use the date of manufacturing for the calculation. Keep container dry and tightly closed.

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    The information presented herein is believed to be accurate and reliable but is presented without guarantee or responsibility on the part of Albemarle Corporation and its subsidiaries and affiliates. It is the responsibility of the user to comply with all applicable laws and regulations and to provide for a safe workplace. The user should consider any health or safety hazards or information contained herein only as a guide and should take those precautions which are necessary or prudent to instruct employees and to develop work practice procedures in order to promote a safe work environment. Further, nothing contained herein shall be taken as an inducement or recommendation to manufacture or use any of the herein materials or processes in violation of existing or future patent.