Phenylmagnesium Chloride, typ. 25 % solution in THF (typ. 1.9 M)
C6H5ClMg
Phenylmagnesium Chloride (CAS 100-59-4) is an organomagnesium compound (Grignard reagent) with molecular formula C6H5ClMg. It is supplied as a typical 25% solution in THF.
In organic synthesis it is used in Grignard-type reactions as a reactive carbon nucleophile.
Phenylmagnesium Chloride reacts readily with moisture and oxygen and should be handled under dry, inert conditions. Consult the SDS and site-specific procedures for compatible materials, fire response, and storage.
Applications
Grignard-reactions: reagent for the introduction of the phenyl group.
Specifications
- Phenylmagnesium Chloride: 24.0– 26.0 %
Method of Analysis
Determination of assay as total base by acidimetric titration after hydrolysis; detailed description available on request.Handling Instructions
Phenylmagnesium Chloride should only be handled under inert gas atmosphere. Avoid contact with eyes, skin and clothes as well as inhalation. Vapors may form explosive mixtures with air. Vapors are heavier than air and may spread along floors. Flash-back possible over considerable distance. Use only explosion-proof equipment. Take measures against electrostatic discharges. Protect from frost, heat and sunlight. Never add water, acids or oxidizing materials to the product. In case of fire use dry extinguishers on basis of sodium chloride or limestone powder. Never use water or CO2-extinguishers. Pay attention to the safety data sheet.
Storage Instructions
Phenylmagnesium Chloride should be stored in tightly closed containers under exclusion of air and humidity. As material tends to crystallize at lower temperatures, it should be stored above 15 °C. When stored according to SDS the material is fairly stable. We still recommend to retest the material 6 months after date of analysis if included on CoA. If not included, use the date of manufacturing for the calculation.
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