Methyllithium, typ. 3 % solution in 2-Methyl-THF / Cumene
C-H3-Li
Methyllithium (CAS 917-54-4) is an organolithium reagent with molecular formula CH3Li. It is supplied as a typical 3% solution in 2-Methyl-THF / Cumene.
Methyllithium is commonly used as a strong base or nucleophile in organic synthesis. Typical applications include alkylation, deprotonation and halogen-lithium exchange.
Methyllithium reacts readily with moisture and oxygen and should be handled under dry, inert conditions. Consult the SDS and site-specific procedures for compatible materials, fire response, and storage.
Applications
Alkylating and metalating agent.
Specifications
- Methyllithium: 2.7 - 3.4 %
- Cumyllithium: max. 1 Mol%
- Heptane: max. 1%
- MTHF/Methyllithium: 1,9 - 2,1 / 1
- Appearance: yellow to amber solution
Method of Analysis
Determination of assay as total base by colorimetric titration. Determination of Cumyllithium, Heptane and MTHF/Methyllithium quotient by GC. Detailed description available on request.Handling Instructions
Handling only under inert gas (nitrogen or argon). Protect from moisture and water. Product is spontaneously flammable in air. Wear personal protective equipment. Take precautionary measures against static discharge. Pay attention to official safety regulations (see also: “Transport regulations“ and “Marking“).
Storage Instructions
Keep container tightly closed in a dry, cool and well ventilated place Best in a cold- storage depot or refrigerator. Keep away from sources of ignition. Take precautionary measures against static discharges. When stored according to SDS the material has limited stability due to decomposition over time. We therefore recommend to retest the material 6 months after date of analysis if included on CoA. If not included, use the date of manufacturing for the calculation.
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