Lithium tert-Amoxide, typ. 40 % solution in Heptane (typ. 3.1 M)
C5H11OLi
Lithium tert-Amoxide (CAS 53535-81-2) is a metal alkoxide with molecular formula C5H11OLi. It is supplied as a typical 40% solution in Heptane.
It is commonly used as a moderately strong base for selective deprotonation and related transformations.
Lithium tert-Amoxide reacts readily with moisture and oxygen and should be handled under dry, inert conditions. Consult the SDS and site-specific procedures for compatible materials, fire response, and storage.
Applications
Deprotonation reactions in organic synthesis.
Specifications
- Lithium tert-Amoxide 39 - 41 %
- LiOH + Li2CO3 max. 0.5 % *)
- calculated as LiOH
- Color colorless to grey yellow
- Appearance clear to turbid
- Aggregate liquid
Method of Analysis
Determination of total base by potentiometric titration of the hydrolyzed product. Detailed description available on request. Determination of LiOH by Karl Fischer titration.Handling Instructions
Lithium tert-Amoxide should be handled under inert gas atmosphere. Avoid contact with eyes, skin and clothes as well as inhalation. Vapors may form explosive mixtures with air. Vapors are heavier than air and may spread along floors. Flash- back possible over considerable distance. Use only explosion-proof equipment. Take measures against electrostatic discharges. Protect from frost, heat and sunlight. Lithium tert-Amoxide decomposes in contact with humidity. In case of fire use dry extinguishers on basis of sodium chloride or limestone powder. Never use water or CO2-extinguishers. Pay also attention to the Safety Data Sheet.
Storage Instructions
Lithium tert-Amoxide should be stored in tightly closed containers under exclusion of humidity at gentle temperatures. The product starts to form crystalline precipitates on cooling below abt. 10 °C. Recommended storage temperature: min. 15 °C. When stored according to SDS the material is fairly stable. We still recommend to retest the material 9 months after date of analysis if included on CoA. If not included, use the date of manufacturing for the calculation. Keep away from heat, sparks and fire. Pay also attention to the Safety Data Sheet.
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