tert-Butyllithium, typ. 18 % solution in Pentane (typ. 1.9 M)
C4H9Li
tert-Butyllithium (CAS 594-19-4) is an organolithium reagent with molecular formula C4H9Li. It is supplied as a typical 18% solution in Pentane.
tert-Butyllithium is commonly used as a strong base and nucleophile in organic synthesis. Typical applications include alkylation, deprotonation and also halogen-lithium exchange.
tert-Butyllithium reacts readily with moisture and oxygen and should be handled under dry, inert conditions. Consult the SDS and site-specific procedures for compatible materials, fire response, and storage.
Applications
Alkylating and metalating agent. Reagent for the introduction of the tert-butyl group.
Specifications
- tert-Butyllithium: 17 - 19 %
Method of Analysis
Determination of assay as active base. Detailed description available on request.Handling Instructions
Handling only under inert gas (nitrogen or argon). The product may ignite spontaneously on contact with air, especially if the solvent is evaporated quickly. Therefore the danger of ignition is enhanced if the solution comes in contact with surface rich materials (paper, textiles) or if it is sprayed. Pay attention to official safety regulations (see also: "Transport regulations" and "GHS Hazard Pictograms", especially fire-fighting).
Storage Instructions
Under exclusion of air and humidity the solution is fairly stable. To keep the quality a storage of 0-10 °C is recommended. The solution should be stored in tightly closed containers in a well ventilated cool place.
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