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Ethylmagnesium Chloride, typ. 25 % solution in THF (typ. 2.8 M)

Ethylmagnesium Chloride, typ. 25 % solution in THF (typ. 2.8 M)

C2-H5-Cl-Mg

CAS Number:  2386-64-3 EC Number:  219-206-9 REACH Number:  01-2120065577-46-0000

Ethylmagnesium Chloride (CAS 2386-64-3) is an organomagnesium compound (Grignard reagent) with molecular formula C2-H5-Cl-Mg. It is supplied as a typical 25% solution in THF.

In organic synthesis it is used in Grignard-type reactions as a reactive carbon nucleophile or in deprotonation reactions as a base.

Ethylmagnesium Chloride reacts readily with moisture and oxygen and should be handled under dry, inert conditions. Consult the SDS and site-specific procedures for compatible materials, fire response, and storage.

Physical and Chemical Properties
Property Value
IUPAC Name
Chloroethylmagnesium
Molecular Weight
88.82g/mol
Appearance
Liquid
Color
Yellow To Dark Brown
Flash Point
-21.2 °C 1,013 hPa (Tetrahydrofuran)
Boiling Point
65 °C at 1,013 hPa (Tetrahydrofuran)
Density
ca. 1.0 g/cm3 at 20 °C
Solubility in Water
(Not applicable)
Thermal Stability
Crystallisation below around 5 °C

Applications

Grignard-reactions: reagent for the introduction of the ethyl group.

Specifications

  • Ethylmagnesium Chloride: 24.0 – 26.0 %

    Method of Analysis

    Determination of assay as total base by acidimetric titration after hydrolysis; detailed description available on request.

    Handling Instructions

    The material should only be handled under inert gas atmosphere. Vapors may form explosive mixtures with air. Vapors are heavier than air and may spread along floors. Flash back possible over considerable distance. Use only explosion-proof equipment. Protect from frost, heat and sunlight. Never add water, acids, oxidizing materials or alcohols. In case of fire use dry extinguishers based on sodium chloride or limestone powder, never use water or CO2. Pay attention to the Safety Data Sheet - Section 7.

    Storage Instructions

    When stored according to SDS the material is fairly stable. We still recommend to retest the material 6 month after date of analysis if included on CoA. If not included, use the date of manufacturing for the calculation. As material tends to crystallize at lower temperatures, it should be stored above 15 °C.

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    The information presented herein is believed to be accurate and reliable but is presented without guarantee or responsibility on the part of Albemarle Corporation and its subsidiaries and affiliates. It is the responsibility of the user to comply with all applicable laws and regulations and to provide for a safe workplace. The user should consider any health or safety hazards or information contained herein only as a guide and should take those precautions which are necessary or prudent to instruct employees and to develop work practice procedures in order to promote a safe work environment. Further, nothing contained herein shall be taken as an inducement or recommendation to manufacture or use any of the herein materials or processes in violation of existing or future patent.