Product Finder

Zinc Bromide, typ. 30 % solution in THF

 
CAS No.7699-45-8
Product No.408621
EINECS231-718-4
 

Application

The use of a 'ready-made' THF solution avoids the handling of the very hygroscopic and dusty ZnBr2 powder.



The ZnBr2 THF solution was developed mainly for the application in organic synthesis, e.g.:



- transmetallation of organomagnesium and organolithium compounds to the corresponding zinc reagents for C-C coupling reactions (Negishi protocol).
- formation of zinc enolates by deprotonation of carbonyl compounds using standard bases followed by transmetallation with ZnBr2.
- catalysis of cycloaddition reactions e.g. Diels-Alder reactions of electron rich dienes with carbonyl compounds.
- preparation of selective reducing agents, e.g. Zn(BH4)2 by reaction of NaBH4 with ZnBr2.



Reference:
McGarvey, G.J. in Encyclopedia of Reagents for Organic Synthesis, Paquette, L.A., Ed. John Wiley and Sons, New York (1995), Vol. 8, 5544.

 
Download Technical Datasheet